Snyder, D.T.; Panczyk, E.M.; Somogyi, A.; Kaplan, D.; Wysocki, V.H. Simple and Minimally Invasive SID Devices for Native Mass Spectrometry.
Anal Chem., 2020, epub July 23, 2020. https://doi.org/10/1021/acs.analchem.0c01657
Chen, Z.; Kibler, R.D.; Hunt, A.; Busch, F.; Pearl, J.; Jia, M.; VanAernum, Z.L.; Wicky, B.I.M.; Dods, G.; Liao, H.; Wilken, M.S.; Ciarlo, C.; Green, S.; ElpSamad, H.; Stamatoyannopoulos, J.; Wysocki, V.H.; Jewett, M.C.; Boyken, S.E.; Baker, D., De Novo Design of Protein Logic Gates.
Science, 03 April 2020, 368, 6486, 78-84. DOI: 10.1126/science.aay2790
Stiving, A. Q.; Gilbert, J. D.; Jones, B. J.; Wysocki, V. H.; A Tilted Surface and Ion Carpet Array for SID.
Anal. Chem. 2020, 31, 458-462. DOI: 10.1021/jasms.9b00009
Vimer, S.; Ben-Nissan, G.; Morgenstern, D.; Kumar-Deshmukh, K.; Polkinghorn, C.; Quintyn R.S.; Vsil’ev, Y.V.; Beckman, J.S.; Elad, N.; Wysocki, V.H.; Sharon, M.; Comparative Structural Analysis of 20S Proteasome Ortholog Protein Complexes by Native Mass Spectrometry.
ACS Cent. Sci. 2020, 6, 573-588. DOI:10.1021/acscentsci.0c00080
Zheng, X.; Kurulugama, R. T.; Laganowsky, A.; Russell, D.H.; Collision-Induced Unfolding Studies of Proteins and Protein Complexes using Drift Tube Ion Mobility-Mass Spectrometer.
Anal. Chem. 2020, 92, 10, 7218–7225. DOI: 10.1021/acs.analchem.0c00772
Simmonds, A. L.; Lopez-Clavijo, Andrea F.; Winn, P. J.; Russell, D. H.; Styles, I. B.; Cooper, H. J.; Structural Analysis of 14-3-3-ζ-Derived Phosphopeptides Using Electron Capture Dissociation Mass Spectrometry, Traveling Wave Ion Mobility Spectrometry, and Molecular Modeling.
J. Phys. Chem. B 2020, 124, 3, 461-469. DOI: 10.1021/acs.jpcb.9b08506 .
Stiving AQ, Jones BJ, Ujma J, Giles K, Wysocki VH. Collision Cross Sections of Charge Reduced Proteins and Protein Complexes: A Database for Collision Cross Section Calibration.
Anal. Chem. 2020 March 17;92(6):4475-4483. PubMed PMID: 32048834; PubMed Central PMCID: PMC7170229; DOI: 10.1021/acs.analchem.9b05519.
Jia, M.; Sen, S.; Wachnowsky, C.; Fidai, I.; Cowan, J.A. and Wysocki, V.; Characterization of [2Fe‐2S]‐Cluster‐Bridged Protein Complexes and Reaction Intermediates by use of Robust Native Mass Spectrometric Methods.
Angewandte Chemie International Edition. 2020, DOI: 10.1002/anie.201915615
Lin, C.; McCabe, J. W.; Russell, D. H.; Barondeau, D. P.; Molecular mechanism of ISC iron-sulfur cluster biogenesis revealed by high-resolution native mass spectrometry.
J. Am. Chem. Soc. 2020, 142, 13, 6018-6029. DOI: 10.1021/jacs.9b11454
Shirzadeh, M.; Poltash, M.L.; Laganowsky, A.; Russell, D.H., Structural Analysis of the Effect of Dual-FLAG Tag on Transthyretin.
Biochemistry, 2020, 59, 9, 1013-1022. DOI: 10.1021/acs.biochem.0c00105.
Kristoff, C.J.; Li, C.; Li, P.; Holland, L.A. Low flow voltage free interface for capillary electophoresis and mass spectrometry driven by vibrating sharp-edge spray ionization.
Anal. Chem. 2020, 92, 4, 3006-3013. DOI: 10.1021/acs.analchem.9b03994
Panczyk, E.M.; Gilbert, J.D.; Jagdale, G.S.; Stiving, A.Q.; Baker, L.A. and Wysocki, V.H.;Ion Mobility and Surface Collisions: Submicrometer Capillaries Can Produce Native-like Protein Complexes.
Anal. Chem., 2020 Feb 4; 92(3):2460-2467 DOI:10.1021/acs.analchem.9b03666.
Norris, A.; Busch, F.; Schupfner, M.; Sterner, R.; Wysocki, V.H. Quaternary structure of the tryptophan synthase α-subunit homolog BX1 from Zea mays,
J. Am. Soc. Mass. Spectrom., 2020 Feb 5; 31(2):227-233. DOI: 10.1021/jasms9b00068
VanAernum, Z.; Busch, F.; Jones, B.J.; Jia, M.; Chen, Z.; Boyken, S.E.; Sahasrabuddhe, A.; Baker, D.; Wysocki, V. Rapid Online Buffer Exchange: A Method for Screening of Proteins, Protein Complexes, and Cell Lysates by Native Mass Spectrometry.
Nature Protocols 2020, DOI: 10.1038/s41596-019-0281-0
Poltash, M.L.; McCabe, J.W.; Shirzadeh, M.; Laganowsky,; Russell, D.H., Native IM-Orbitrap MS: Resolving what was hidden.
Trends in Analytical Chemistry, 2020, 124:115533. DOI: https://doi.org/10.1016/j.trac.2019.05.035
Purde, V.; Busch, F.; Kudryashova, E.; Wysocki, V.H.; Kudryashov, D.S., Oligomerization affects the ability of human cyclase associated proteins 1 and 2 to promote actin severing by cofilins.
Int. J. Molecular Sciences, 2019, 20, 5647
Kneuttinger, A.; Zwisele, S.; Straub, K.; Bruckmann, A.; Busch, F.; Kinateder, T.; Gaim, B.; Wysocki, V.; Merkl, R.; Sterner, R. Light-Regulation of Tryptophan Synthase by Combining Protein Design and Enzymology.
Int. J. Molecular Sciences. 2019, 20, 5106.
Kneuttinger, A.C.; Straub, K.; Bittner, P.; Simeth, N.A.; Bruckmann, A.; Busch, F.; Rajendran, C.; Hupfeld, E.; Wysocki, V.H.; Horinek,D.; König, B.; Merkl, R.; Sterner, R. Light regulation of enzyme allostery through photo-responsive unnatural amino acids.
Cell Chemical Biology 2019, 19, 30271-5.
Snyder, D. T.; Panczyk, E.; Stiving, A. Q.; Gilbert, J.; Somogyi, A.; Kaplan, D.; Wysocki, V. Design and performance of a second-generation surface-induced dissociation cell for Fourier transform ion cyclotron resonance mass spectrometry of native protein complexes.
Anal. Chem. 2019, 91, 14049-14057. DOI: 10.1021/acs.analchem.9b03746
Moghadamchargari Z, Huddleston J, Shirzadeh M, Zheng X, Clemmer DE, M Raushel F, Russell DH, Laganowsky A. Intrinsic GTPase Activity of K-RAS Monitored by Native Mass Spectrometry.
Biochemistry. 2019 Aug 6;58(31):3396-3405. doi:10.1021/acs.biochem.9b00532.
Seffernick, J.T.; Harvey, S.R.; Wysocki, V.H.; Lindert, S. Predicting protein complex structure from surface-induced dissociation mass spectrometry data.
ACS Cent Sci, 2019, 5 (8), 1330-1341.
Boyken, S.E.; Benhaim, M. A.; Busch, F.; Jia, M.; Bick, M. J.; Choi, H.; Klima, J. C.; Chen, Z.; Walkey, C.; Mileant, A.; Sahasrabuddhe, A.; Wei, K. Y.; Hodge, E. A.; Byron, S.; Quijano-Rubio, A.; Sankaran, B.; King, N. P.; Lippincott-Schwartz, J.; Wysocki, V. H.; Lee, K.K.; Baker D., De novo design of tunable, pH-driven conformational changes.
Science, 2019, 364(6441):658-664. DOI: 10.1126/science.aav7897.
Schupfner, M.; Busch F.; Wysocki, V.; Sterner, R., Generation of a stand-alone tryptophan synthase α-subunit by mimicking an evolutionary blueprint.
Chembiochem, 2019,20,2747-2751. DOI: 10.1002/cbic.201900323.
Woodall, D.W.; El-Baba, T.J.; Fuller, D.R.; Liu, W.; Brown, C.J.; Laganowsky, A.; Russell, D.H.; Clemmer, D.E., Variable-Temperature ESI-IMS-MS Analysis of Myohemerythrin Reveals Ligand Losses, Unfolding, and a Non-Native Disulfide Bond.
Anal. Chem., 2019, 91,10,6808-6814. DOI: 10.1021/acs.analchem.9b00981
Liu, Y.; LoCaste, C.E.; Liu, W.; Poltash, M.L.; Russell, D.H.; Laganowsky, A., Selective binding of a toxin and phosphatidylinositides to a mammalian potassium channel.
Nature Communications, 2019 Mar 22;10(1):1352. DOI 10.1038/s41467-019-09333-4.
VanAernum, Z.L.; Gilbert, J.D.; Belov, M.E.; Makarov, A.A; Horning, S.R.; Wysocki, V.H.; Surface-Induced Dissociation of Noncovalent Protein Complexes in an Extended Mass Range Orbitrap Mass Spectrometer.
Anal. Chem., 2019, 91, 3, 2345-2351. DOI: 10.1021/acs.analchem.8b05605.
Poltash, M.L.; Shirzadeh, M.; McCabe, J.W.; Moghadamchargari, Z.; Langanowsky, A.; Russell, D.H., New insights into a the metal-induced oxidative degradation pathways of transthyretin.
Chemical Communications, 2019, 55, 4091-4094. DOI 10.1039/C9CC00682F.
Harvey, S.R.; Seffernick, J.T.; Quintyn, R.S.; Song, Y.; Ju, Y; Yan, J.; Sahasrabuddhe, A.N.; Norris, A.; Zhou, M.; Behrman, E.J.; Lindert, S; Wysocki, V.H., Relative interfacial cleavage energetics of protein complexes revealed by surface collisions.
PNAS, 2019; 116 (17)8143-8148. DOI 10.1073/pnas.1817632116.
Poltash, M.L.; McCabe, J.W.; Shirzadeh, M.; Laganowsky, A.; Clowers, B.H.; Russell, D.H.,Fourier Transform-Ion Mobility-Orbitrap Mass Spectrometer: A Next-Generation Instrument for Native Mass Spectrometry..
Anal. Chem., 2018, 2018, 90,10472-10478. doi: 10.1021/acs.analchem.8b02463.
Stiving, A. Q.; VanAernum Z.; Busch, F.; Harvey S. R.; Sarni, S.; Wysocki, V. H., Surface-Induced Dissociation: An Effective Method for Characterization of Protein Quaternary Structure.
Anal Chem., 2019, 91, 190-209. DOI:10.1021/acs.analchem.8b05071.
Shirzadeh, M.; Boone, C.D.; Laganowsky, A.; Russell, D.H., Topological Analysis of Transthyretin Disassembly Mechanism: Surface-Induced Dissociation Reveals Hidden Reaction Pathways.
Analytical Chemistry, 2019, 91, 3, 2345-2351 DOI:10.1021/acs.analchem.8b05066
Chen, Z.; Boyken, S.; Jia, M; Busch, F; Flores-Solis, D.; Bick, M.J.; Lu, P; VanAernum, Z. L.; Sahasrabuddhe, A; Langan, R. A.; Bermeo S.; Brunette, T.J.; Mulligan, V. K.; Carter, L.P.; DiMaio, F.; Sgourakis, N.G.; Wysocki, V.H.; Baker,D.,Programmable design of orthogonal protein heterodimers.
Nature. 2018; Epub ahead of print. DOI:https://doi.org/10.1038/s41586-018-0802-y.
